PRIMD

Pramipexole Research on Impacts on Motivational Drive

Key Info

We are looking for people aged 18-45 both with and without symptoms of low motivation to take part in a study investigating the effects of a licensed drug on the brain.

Location

Warneford Hospital, OX3 7JX

Group

People aged 18-45 with or without symptoms of low motivation

Ethics Reference

MS IDREC 869455

What does this involve?

In this study, we will use a series of psychological tests to explore how pramipexole, a drug that affects the chemical dopamine in the brain, affects behaviour, especially when it comes to motivation. As part of the study, you will receive either pramipexole (an antidepressant drug) or a placebo (a dummy treatment). Before and 12 to 15 days after the treatment, you will be invited to complete a series of questionnaires and psychological tasks. 

Who are we looking for?

We are looking for individuals aged 18-45 years old, with or without current symptoms of apathy (loss of motivation). Please note: We will be unable to include you if you have taken part in any other drug studies in the past 3 months, including if you are currently enrolling in one. We will also be unable to include you if you have taken part in any other  PERL  studies in the past  6 months, including if you are currently enrolling in one.

How do I learn more?

Complete our pre-screening questionnaire below or email us at primdstudy@psych.ox.ac.uk

Sign Up Here!

If you are interested in taking part, please follow the link below to complete our initial screening survey. Alternatively, please email us at primdstudy@psych.ox.ac.uk.  

What studies am I eligible for?

Check whether you would be eligible for any of our current studies! You may be asked a few questions about your mood and demographics. All of your responses are completely anonymous and will not be kept on our records.

Thank you for your interest!

If you are experiencing low moods or depression and would like advice or support, please read our mental health support page.